Ldspharma

Mydoeln-10 ® Capsules

(Lenalidomide 10mg)

GENERIC NAME: Lenalidomide 10mg Capsules

THERAPEUTIC CLASS: Immunomodulatory agents

INDICATIONS & DOSAGE:

  • Multiple myeloma (MM), in combination with dexamethasone, in patients who have received at least one prior therapy
  • Transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q abnormality with or without additional cytogenetic abnormalities
  • Mantle cell lymphoma (MCL) whose disease has relapsed or progressed after two prior therapies, one of which included bortezomib

STORAGE: Store below 30°C. Protect from sunlight.

PACK SIZE:  1×1’s

DOSAGE & ADMINISTRATION:

MM: 25 mg once daily orally on Days 1-21 of repeated 28-day cycles.

Recommended dose of dexamethasone is 40 mg once daily on Days 1-4, 9-12, and 17-20 of each 28-day cycle for the first 4 cycles of therapy and then 40 mg/day orally on Days 1-4 every 28 days

  • MDS: 10 mg once daily
  • MCL: 25 mg once daily orally on Days 1-21 of repeated 28-day cycles
  • Continue or modify dosing based on clinical and laboratory findings
  • Renal impairment: Adjust starting dose in patients with moderate or severe renal impairment and on dialysis