Pegaspa ® 3750 IU/ 5ml Injection
(PEG-L-Asperginase 3750 IU/5ml)
GENERIC NAME: Peg-L-Asparaginase 3750 IU/5ml
THERAPEUTIC CLASS: Antineoplastic Agent
INDICATIONS & DOSAGE:
- First Line Acute Lymphoblastic Leukemia (ALL)
- Hypersensitivity to native forms of L-asparaginase
STORAGE: Store at 2 to 8 °C. Protect from sunlight.
STRENGTH: Injection: 3,750 International Units/5 mL (3750 International Units/mL) solution in a single-dose vial.
PACK SIZE: 1×1’s
DOSAGE & ADMINISTRATION:
Administered intramuscularly or intravenously no more frequently than every 14 days.
- Patients ages 21 years and younger: 2,500 International Units/m2
- Patients ages over 21 years: 2,000 International Units/m2
- For intramuscular administration, limit the volume at a single injection site to 2 mL; if greater than 2 mL, use multiple injection sites.
- For intravenous administration, give over a period of 1 to 2 hours in 100 mL of 0.9% Sodium Chloride Injection, USP, or 5% Dextrose Injection, USP through an infusion that is already running.
- Do not administer, if the drug has been frozen, stored at room temperature for more than 48 hours, or shaken or vigorously agitated.